Current flagship. 1.5x B200 memory and FP4 compute, built for reasoning-era inference: long contexts and fat KV caches. Ships in GB300 NVL72 racks.
GPU & Workload Guide
NVIDIA GPU reference for ML inference — hardware specs, workload patterns, and the interconnects that tie them together. Updated July 2026.
Start here
| You're serving | Start with | Why |
|---|---|---|
| Up to 8B | One L4 or A10G at FP8 | 8B at FP8 is ~10GB, so a 24GB card leaves room for KV cache. T4 still fine for embeddings. |
| 13–34B | L40S at FP8, or A100 80GB | 34B at FP8 is ~41GB. GDDR6 bandwidth is the tradeoff you accept for the price. |
| 70B class | H200 at FP8, or 2× H100 | 70GB of weights makes an 80GB card tight once context grows; 141GB is comfortable. |
| 100–405B | 4–8× H100/H200, or 2–4× B200 at FP4 | Tensor parallel over NVLink. FP4 halves the footprint if you're on Blackwell. |
| 600B+ frontier MoE | 8× B300, or NVL72 territory | R1-class MoEs load total parameters, not active ones. This is rack-scale serving. |
Will it fit?
| GPU | Memory | Setup |
|---|
GPU types
The volume Blackwell. 2.5x H100 performance; what most GB200 NVL72 racks are made of.
Blackwell mainstream on paper. In practice the market skipped straight to B200 — you will rarely see one.
H100 with more memory. Better for 70B-405B models. 1.4x H100 bandwidth.
The fleet workhorse. Still what clouds have in volume, and the price/performance default for 70B-class serving.
Previous-generation workhorse. Increasingly the value pick as fleets turn over to Hopper and Blackwell.
High-memory inference. Llama 70B single GPU, large context windows, vision-language models.
Large memory capacity. Multi-modal models, large batch inference, video generation.
Cost-effective inference. Llama 7B/13B, Whisper, smaller vision models, embeddings.
Graphics-heavy workloads. ControlNet, image generation, video processing.
Entry-level inference. Small language models, embeddings, classification, lightweight tasks.
Older generation. Still viable for many inference workloads at lower cost.
On the horizon
Next architecture, paired with the Vera CPU. Numbers are NVIDIA's keynote claims, not benchmarks — treat as direction, not spec.
Workload patterns
Single GPU
Most common inference pattern. Model fits entirely in one GPU's memory. Simple, fast, cost-effective.
Llama 3.1 8B, Qwen2.5 7B, Whisper, SDXL, embedding and reranker models
Multi-GPU (2x)
Tensor parallelism splits model across 2 GPUs. Needed when model exceeds single GPU memory. Requires fast interconnect.
Llama 3.3 70B, Qwen2.5 72B, large vision-language models
Multi-GPU (4x+)
Large-scale tensor parallelism for massive models. 4-8 GPUs with NVLink. High complexity, high cost, highest capability.
Llama 3.1 405B, DeepSeek-R1 671B, frontier-scale MoEs
GPU connectivity
NVLink
When it matters: multi-GPU inference for 70B+ models. NVLink enables efficient tensor parallelism by allowing fast weight sharing across GPUs. Critical for maintaining low latency at scale.
PCIe Gen5
When it matters: fine for single-GPU inference and model loading (Hopper and Blackwell are Gen5 parts). Becomes the bottleneck for multi-GPU tensor parallelism — that is what NVLink is for.
NVSwitch
When it matters: full bisection bandwidth between any GPU pair. The GB200/GB300 NVL72 puts 72 Blackwells in one NVLink domain — the unit of account for frontier serving. Expensive but necessary at that scale.